JAB1 (COPS5) (N-term) Rabbit Polyclonal Antibody

CAT#: AP31028PU-N

JAB1 (COPS5) (N-term) rabbit polyclonal antibody, Purified

Product Images

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 1/100.
  Western Blot: 1 - 2 µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide from N-terminal of human JAB1 protein
• Specificity: This antibody reacts to the N-term of 38 Kda Mov34 Isologue (COPS5).
• Formulation: 10 mM PBS, pH 7.4 containing BSA as stabilizer and 0,09% sodium azide as preservative
  State: Purified
  State: Liquid purfied Ig fraction
• Concentration: 0.2 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens COP9 signalosome subunit 5 (COPS5)
• Database Link:
  Entrez Gene 26754 MouseEntrez Gene 312916 RatEntrez Gene 10987 Human
• Background: Jun activation domain-binding protein-1 (JAB1) also designated COP9 subunits 5 (COPS5) or SGN5 is a coactivator of AP-1 transcription factor that also promotes degradation of the cyclin-dependent kinase inhibitor p27Kip1. JAB1 interacts with c-Jun AP-1 containing complexes, and enhances transactivation from AP-1-dependent promoters. JAB1 is highly conserved in evolution and is widely expressed in mammalian tissues. It is localized both the nucleus and the cytoplasm.
• Synonyms: Signalosome subunit 5, SGN5, CSN5, JAB1

Reference Data

• Protein Families: Druggable Genome, Protease, Transcription Factors