NOTCH1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP31032PU-N

NOTCH1 (C-term) rabbit polyclonal antibody, Purified

Product Images

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide from C-terminal of human notch-1
• Specificity: This antibody reacts to the C-term of Notch Homolog 1, Translocation-associated (NOTCH1).
• Formulation: 10 mM PBS, pH 7.4 containing BSA as stabilizer and 0,09% sodium azide as preservative
  State: Purified
  State: Liquid purfied Ig fraction
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens notch 1 (NOTCH1)
• Database Link:
  Entrez Gene 4851 Human
• Background: The 280-330kDa Notch proteins have been found to be overexpressed or rearranged in human tumors ligands for Notch include Jagged, Jagged-2 and Delta. Jagged can activate Notch and prevent myoblast differentiation by inhibiting the expression of muscle regulatory and structural genes.
• Synonyms: Notch 1, hN1, TAN1

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway
• Protein Pathways: Dorso-ventral axis formation, Notch signaling pathway, Prion diseases