TNFRSF1B (C-term) Rabbit Polyclonal Antibody

CAT#: AP31209PU-N

TNFRSF1B (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Formalin-Fixed, Paraffin-Embedded Human Placenta stained with TNFR2 antibody Cat.-No AP31209PU-N at 1/50 dilution after heat-induced antigen retrieval.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 1/50.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from C-terminal of Mouse TNF-R2
• Specificity: This antibody recognizes the C-term of TNFRSF1B / TNFR2.
• Formulation: 10 mM PBS, pH 7.4, BSA, 0.09% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens TNF receptor superfamily member 1B (TNFRSF1B)
• Database Link:
  Entrez Gene 21938 MouseEntrez Gene 156767 RatEntrez Gene 7133 Human
• Background: TNFR2 is a 75 kD transmembrane glycoprotein that also exists as a secreted protein. TNF receptors self assemble through a distinct functional extracellular domain termed PLAD in the absence of ligand. Efficient TNFA binding depends on receptor self assembly. TNFR2 has been shown to be responsible for stimulation of activated T lymphocytes by TNFalpha.
• Synonyms: Tumor necrosis factor receptor 2, p80 TNF-alpha receptor, TNFRSF1B, TNFBR, TNF-R2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Amyotrophic lateral sclerosis (ALS), Cytokine-cytokine receptor interaction