PREX1 (1514-1526) Goat Polyclonal Antibody

CAT#: AP31278PU-N

PREX1 (1514-1526) goat polyclonal antibody, Aff - Purified

Product Images

PREX1 antibody (1 ug/ml) staining of Human Temporal Cortex lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• 

  Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/16000.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1 - 3 µg/ml.
• Reactivities: Bovine, Bat, Canine, Human, Monkey
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of Human PREX1 (NP_065871.2)
• Specificity: This antibody reacts to the internal region of PREX1.
• Formulation: Tris saline buffer, pH~7.3
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Stabilizer: 0.5% BSA
  Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1)
• Database Link:
  Entrez Gene 277360 MouseEntrez Gene 311647 RatEntrez Gene 57580 Human
• Background: Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
• Synonyms: P-Rex1, KIAA1415

Reference Data

• Protein Pathways: Chemokine signaling pathway