Catalase (CAT) Rabbit Polyclonal Antibody

CAT#: AP31325PU-N

Catalase (CAT) rabbit polyclonal antibody, Purified

Product Images

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/20000.
  Immunohistochemistry on Paraffin Sections: 1/100.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated
• Specificity: This antibody detects endogenous levels of total Catalase protein.
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens catalase (CAT)
• Database Link:
  Entrez Gene 12359 MouseEntrez Gene 24248 RatEntrez Gene 847 Human
• Background: Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen.Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size.Catalase has been implicated as an important factor in inflammation,mutagenesis, preven-tion of apoptosis, and stimulation of a wide spectrum of tumors.Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara’s disease.
• Synonyms: CAT, Peroxisome Marker

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Metabolic pathways, Methane metabolism, Tryptophan metabolism