PPP3CC (N-term) Rabbit Polyclonal Antibody

CAT#: AP31353PU-N

PPP3CC (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot of hPPP3CC-E33 AP31353PU-N in HL-60, Jurkat, A375 cell line lysates (35 ug/lane). PPP3CC (arrow) was detected using the purified Pab.

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  Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: kLH conjugated synthetic peptide selected from the N-terminal region of Human PPP3CC.
  Epitope: N-Terminus.
• Specificity: This antibody detects PPP3CC (N-term).
• Formulation: PBS containing 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Purification: Ammonium Sulfate Precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 2
• Database Link:
  Entrez Gene 5533 Human
• Background: Calcineurin A gamma (PPP3CC), a PP2B type serine/threonine phosphatase, is a catalytic subunit of calcineurin which acts as a calcium dependent modifier of phosphorylation status. It is believed to function in the calmodulin activation of calcineurin. Additionally, PPP3CC has been shown to be testis-specific in mouse and is believed to be involved in mammalian germ cell function.
• Synonyms: CAM-PRP catalytic subunit, CNA3, protein phosphatase 2B catalytic subunit gamma

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Axon guidance, B cell receptor signaling pathway, Calcium signaling pathway, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway