eNOS (NOS3) (1181-1194) Rabbit Polyclonal Antibody

CAT#: AP31361PU-N

eNOS (NOS3) (1181-1194) rabbit polyclonal antibody, Purified

Product Images

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).

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  Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human, Monkey, Rabbit
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: kLH-conjugated, synthetic peptide corresponding to amino acids 1181-1194 of Human eNOS/NOS III
• Specificity: Recognizes eNOS/NOS III, Mr ~135kD at aa 1181-1194.
• Formulation: PBS, pH 7.6, 0.07% Sodium Azide, before the addition of Glycerol to 30%
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens nitric oxide synthase 3 (NOS3), transcript variant 1
• Database Link:
  Entrez Gene 18127 MouseEntrez Gene 24600 RatEntrez Gene 4846 Human
• Background: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: Endothelial NOS, EC-NOS, NOS type III, Constitutive NOS, eNOS

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Arginine and proline metabolism, Calcium signaling pathway, Long-term depression, Metabolic pathways, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway