Von Willebrand Factor (VWF) Sheep Polyclonal Antibody

CAT#: AP31366FC-N

Von Willebrand Factor (VWF) sheep polyclonal antibody, FITC

Product Images

Human Spleen, Endothelium: Formalin-Fixed, Paraffin-Embedded (FFPE).

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunofluorescence: 1/25 - 1/50.
  Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin Sections: 1/200.
• Reactivities: Human
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Human von Willebrand Factor Antigen (vWF) prepared from citrated Human plasma (>95%).
• Specificity: Recognizes human Von Willebrand Factor (vWF).
  No arcs when tested by IEP against human serum.
  Identity has been confirmed by double diffusion (Ouchterlony) vs. Hhuman vWF and an anti-Human vWF of known specificity.
• Formulation: PBS, pH 7.2 with 0.09% Sodium Azide
  Label: FITC
  State: Liquid purified IgG fraction.
  Label: Fluorescein
• Concentration: lot specific
• Purification: Ion Exchange Chromatography.
• Conjugation: FITC
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens von Willebrand factor (VWF)
• Database Link:
  Entrez Gene 7450 Human
• Background: Von Willebrand Factor (VWF) functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease.
• Synonyms: vWF, von Willebrand antigen 2, von Willebrand antigen II, F8VWF, Factor VIII Related Antigen

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades, ECM-receptor interaction, Focal adhesion