Lactoferrin (LTF) Rabbit Polyclonal Antibody

CAT#: AP31373FC-N

Lactoferrin (LTF) rabbit polyclonal antibody, FITC

Product Images

Human Spleen, Neutrophils: Formalin-Fixed, Paraffin-Embedded (FFPE).

Specifications

Product Data

• Applications: FC, IF, IHC
• Recommended Dilution: Flow Cytometry.
  Immunocytochemistry.
  Immunofluorescence: 1/50 - 1/200.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Purified Lactoferrin from Human colostrum.
• Specificity: Recognizes Human milk Lactoferrin.
  Does not cross-react with other milk or serum proteins.
  This antibody May cross-react with lactoferrin from other species.
• Formulation: Sodium Phosphate, pH 7.2 containing 1 mg/ml BSA as stabilizer and 0.05% Sodium Azide as preservative.
  Label: FITC
  State: Liquid purified IgG fraction.
  Label: Fluorescein
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography.
• Conjugation: FITC
• Storage: Store the antibody undiluted at 2-8°C for one month or (40-50% Add Glycerol) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens lactotransferrin (LTF), transcript variant 2
• Database Link:
  Entrez Gene 4057 Human
• Background: Lactoferrin is an 80kDa non-haem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.
• Synonyms: LTF, LF, Lactoferrin, EC=3.4.21, Talalactoferrin

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein