Desmoglein 1 (DSG1) (841-855) Goat Polyclonal Antibody

CAT#: AP31434PU-N

Desmoglein 1 (DSG1) (841-855) goat polyclonal antibody, Aff - Purified

Product Images

Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/32000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human DSG1 (NP_001933.2)
• Specificity: This antibody reacts to the internal region of DSG1.
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens desmoglein 1 (DSG1)
• Database Link:
  Entrez Gene 1828 Human
• Background: Desmosomes are a type of intercellular junction between epithelial, myocardial, and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein isoforms have been identified: DSG1, DSG2 and DSG3; all members of the cadherin cell adhesion molecule family. DSG1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
• Synonyms: Desmosomal glycoprotein 1, Pemphigus foliaceus antigen, DSG1, CDHF4, DG1, DGI

Reference Data

• Protein Families: Druggable Genome