IL12A Goat Polyclonal Antibody

CAT#: AP31605PU-N

IL12A goat polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications ELISA, IHC
Recommended Dilution ELISA: 1/16000.
Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivities Canine, Human, Monkey
Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide from human IL12A / p35
Specificity Recognizes Interleukin-12 alpha / IL12A.
Formulation Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid freeze-thaw cycles.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens interleukin 12A (IL12A)
Background Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells; costimulation of PBL proliferation; proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10; homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.
Synonyms IL-12A, IL-12 subunit p35, NKSF1, CLMF p35
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.