Complement C5 (C5) Rabbit Polyclonal Antibody

CAT#: AP31672PU-N

Complement C5 (C5) rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: ELISA: 1/2000 - 1/3000.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Specificity: Rabbit Anti-Human C5a polyclonal antibody is prepared by immunizing New Zealand white rabbits with human C5a antigen and isolating the C5a antibody from rabbit serum.
• Formulation: PBS containing 0.02% sodium azide (NaN3) as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens complement C5 (C5), transcript variant 1
• Database Link:
  Entrez Gene 727 Human
• Background: Human C5a is 74 amino acids long and is a potent anaphylatoxin and chemotactic factor that stimulates directed migration of neutrophils, eosinophils, basophils and monocytes. Of all of the anaphylatoxic peptides generated by the activation of the complement system, C5a elicits the broadest range of activity. This activity includes the degranulation of mast cells and basophils, increased vascular permeability and the induction of cytokine synthesis by leukocytes.
• Synonyms: Complement C5 alpha chain, C5a anaphylatoxin, CPAMD4

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus