Myeloperoxidase (MPO) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA |
Recommended Dilution | Western Blot: 1/100. ELISA: 1/70000. |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Native human Myeloperoxidase purified from human Neutrophils |
Specificity | This antibody is specific for the human Myeloperoxidase (MPO). |
Formulation | PBS containing 0.02% sodium azide (NaN3) as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens myeloperoxidase (MPO) |
Database Link | |
Background | Myeloperoxidase (MPO) is a 150KDa lysosomal hemoprotein located in the azurophilic granules of neutrophils and monocytes. MPO is a dimeric protein and each dimer contains a two variable ~60-kD heavy unit and a two12-kD light subunit. MPO is responsible for the microbicidal activity of neutrophils and monocytes against a wide range of organisms. MPO exerts its activity through the production of the cytotoxic compound hypochlorous acid (HOCl) and through generation of tyrosyl radicals on invading organisms. |
Synonyms | MPO |
Reference Data | |
Protein Families | Druggable Genome |
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