GFAP Chicken Polyclonal Antibody

CAT#: AP31737SU-N

GFAP chicken polyclonal antibody, Serum

Product Images

Formalin-Fixed, Paraffin-Embedded Human Brain, Astrocytes stained with GF-N at 1/100 dilution after heat-induced antigen retrieval.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunocytochemistry: 1/100.
  Immunofluorescence: 1/100 - 1/200.
  Immunohistochemistry on Paraffin Sections: 1/100.
  Western Blot: 1/500.
• Reactivities: Human, Mouse
• Host: Chicken
• Isotype: IgY
• Clonality: Polyclonal
• Immunogen: GFAP antibody was raised against full-length recombinant mouse GFAP
• Specificity: Recognizes Mouse GFAP and cross-reacts with Human.
• Formulation: PBS, pH 7.2, 0.02% Sodium Azide as preservative.
  State: Serum
  State: Unpurified Serum
• Concentration: lot specific
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens glial fibrillary acidic protein (GFAP), transcript variant 3
• Database Link:
  Entrez Gene 14580 MouseEntrez Gene 2670 Human
• Background: Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
• Synonyms: Glial Fibrillary Acidic Protein

Reference Data

• Protein Families: ES Cell Differentiation/IPS