ABCB5 Rabbit Polyclonal Antibody

CAT#: AP31746PU-N

ABCB5 rabbit polyclonal antibody, Aff - Purified

Product Images

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 1/1000 - 1/4000.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide
• Specificity: This Polyclonal antibody is directed against Human ABCB5 protein.
  Cross-reactivity with ABCB5 from other sources has not been determined.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1 mg/ml
• Purification: Affinity Chromatography on Protein A
• Gene Name: Homo sapiens ATP binding cassette subfamily B member 5 (ABCB5), transcript variant 1
• Database Link:
  Entrez Gene 340273 Human
• Background: ABCB5 is a plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. ABCB5 is also responsible for the resistance to doxorubicin of a subset of malignant melanomas. ABCB5 has more recently been identified as a marker for human malignant-melanoma-initiating cells.
• Synonyms: ABCB5alpha; ABCB5beta; EST422562

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters