ACAT1 Rabbit Polyclonal Antibody

CAT#: AP31747PU-N

ACAT1 rabbit polyclonal antibody, Aff - Purified

Product Images

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 1/1000 - 1/4000.
• Reactivities: Human, Mouse, Porcine, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide
• Specificity: This Polyclonal antibody is directed against Human ACAT1 protein.
  Cross-reactivity with ACAT1 from other sources has not been determined.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1 mg/ml
• Purification: Affinity Chromatography on Protein A
• Gene Name: Homo sapiens acetyl-CoA acetyltransferase 1 (ACAT1)
• Database Link:
  Entrez Gene 25014 RatEntrez Gene 110446 MouseEntrez Gene 38 Human
• Background: ACAT1 mRNA encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The ACAT gene spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
• Synonyms: ACAT; MAT; T2; THIL

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Butanoate metabolism, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine, leucine and isoleucine degradation