Neurofibromin (NF1) Rabbit Polyclonal Antibody

CAT#: AP31762PU-N

Neurofibromin (NF1) rabbit polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ul

Product Images

Specifications

Product Data
Applications ELISA, IF, IHC, WB
Recommended Dilution ELISA: 1/20000.
Immunofluorescence: 1/100 - 1/500.
Immunohistochemistry on Paraffin Sections.
Western Blot: 1/500 - 1/1000.
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide from Human NF1.
Epitope: Internal.
Specificity This antibody detects endogenous levels of total NF1 protein.
Formulation PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens neurofibromin 1 (NF1), transcript variant 2
Background Mutations linked to neurofibromatosis type 1 led to the identification of NF1. NF1 encodes the protein neurofibromin, which appears to be a negative regulator of the ras signal transduction pathway. In addition to type 1 neurofibromatosis, mutations in NF1 can also lead to juvenile myelomonocytic leukemia. Alternatively spliced NF1 mRNA transcripts have been isolated, although their functions, if any, remain unclear.
Synonyms NF1,NF-1
Reference Data
Protein Families Druggable Genome
Protein Pathways MAPK signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.