PLP1 Chicken Polyclonal Antibody

CAT#: AP31819PU-N

PLP1 chicken polyclonal antibody, Aff - Purified


USD 570.00

2 Weeks*

Size
    • 100 ug

Product Images

Other products for "PLP1"

Specifications

Product Data
Applications IF, IHC
Recommended Dilution Immunocytochemistry.
Immunohistochemistry.
Recommended Dilutions:
1/1000-1/2000 for Immunohistochemistry and Immunocytochemistry using 2% paraformaldehyde-fixed tissues or cells.
Quality Control: The antibody was analyzed by Immunohistochemistry (at a dilution of 1/2000) using Fluorescein-labeled Goat anti-Chicken IgY (1/500 dilution, Cat.-No AP31795FC-N) as the secondary reagent.
Reactivities Human, Mouse
Host Chicken
Isotype Ig
Clonality Polyclonal
Immunogen Synthetic peptide KLH conjugated corresponding to a sequence shared between the Mouse (P60202) and Human (NP_000524) gene products.
Production: After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks, and then affinity-purified using a peptide column. The concentrations of the eluates were then adjusted to 0.1 mg/ml, and the preparation was filter-sterilized.
Specificity Recognizes Proteolipid Protein (PLP).
Formulation 10mM PBS, pH 7.2 containing 0.02% Sodium Azide as preservative.
State: Aff - Purified
State: Liquid purified (filter sterilized) IgY fraction.
Concentration lot specific
Purification Affinity Chromatography using a peptide column.
Storage Store the antibody undiluted in the dark at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens proteolipid protein 1 (PLP1), transcript variant 1
Background Human PLP (also known as lipophilin) is a 29,946 dalton protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in its compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.
Synonyms Myelin proteolipid protein, Lipophilin, PLP
Reference Data
Protein Families Druggable Genome, Transmembrane

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.