Synaptotagmin 1 (SYT1) Chicken Polyclonal Antibody
Other products for "SYT1"
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | Western Blot. Immunocytochemistry. Immunohistochemistry. Recommended Dilutions: 1/2000-1/5000 for Western Blots. 1/1000-1/2000 for Immunohistochemistry and Immunocytochemistry using 2% paraformaldehyde-fixed tissues or cells. Quality Control: Each of the four antibodies was analyzed by Immunohistochemistry (at a dilution of 1/2000) using Fluorescein-labeled Goat anti-Chicken IgY (1/500 dilution, Cat.-No AP31795FC-N) as the secondary reagent. |
Reactivities | Human, Mouse |
Host | Chicken |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | Four different antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_033332) and Human (NP_005630) gene products. Production: After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.4 mg/ml. Finally, equal volumes of each of the four affinity-purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized. Antibodies were affinity-purified and mixed in equal concentrations. |
Specificity | Recognizes Synaptotagmin-1. |
Formulation | 10mM PBS, pH 7.2 containing 0.02% Sodium Azide as preservative. State: Aff - Purified State: Liquid purified (filter sterilized) IgY fraction. |
Concentration | lot specific |
Purification | Affinity Chromatography using a peptide column. |
Storage | Store the antibody undiluted in the dark at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens synaptotagmin 1 (SYT1), transcript variant 2 |
Database Link | |
Background | Human Synaptotagmin-1 is a 47,442 dalton protein (422 amino acids) associated with pre-synaptic terminals of the PNS and CNS. Synaptotagmin-1 binds calcium and initiates the fusion of vesicles with the pre-synaptic membrane. This protein is also believed to be the target of proteolytic activity associated with Botulinum neurotoxin A. |
Synonyms | SYT1, SVP65, SYT, Synaptotagmin1, Synaptotagmin I, SytI, p65 |
Reference Data | |
Protein Families | Secreted Protein, Transmembrane |
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