GHRHR (C-term) Rabbit Polyclonal Antibody

CAT#: AP31828PU-N

GHRHR (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from LOVO cells, using GHRHR antibody. The lane on the right is treated with the synthesized peptide.

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  Formalin-Fixed, Paraffin-Embedded Human Kidney, Tubules stained with GHRHR antibody

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  Immunofluorescence analysis of HuvEc cells, using GHRHR antibody. The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Immunofluorescence: 1/100 - 1/500.
  Immunohistochemistry on Paraffin Sections: 1/200.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from Human GHRHR.
  Epitope: C-Terminus.
• Specificity: This antibody detects endogenous levels of total GHRHR protein.
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens growth hormone releasing hormone receptor (GHRHR)
• Database Link:
  Entrez Gene 14602 MouseEntrez Gene 25321 RatEntrez Gene 2692 Human
• Background: GHRHR, a Growth Hormone-Releasing Hormone Receptor, is involved in the proliferation and differentiation of somatotrophic pituitary cells and in disease. The GHRH receptor stimulates growth hormone (GH) secretion and synthesis in the pituitary. Mutations in this receptor cause either growth-hormone deficiency, resulting in dwarfism, or excessive production of the hormone, leading to gigantism. Four alternative splice variants have been identified that are tissue specific.
• Synonyms: Growth hormone-releasing hormone receptor, GHRHR, GRF receptor, GRFR

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction