JNK2 (MAPK9) (217-230) Goat Polyclonal Antibody
Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | Peptide ELISA: 1/32000 (Detection limit). Western blot: 0.5-1.5µg/ml. Detects a band of Approx 48kDa in Human Brain (Cerebellum) and Mouse Brain lysates. |
Reactivities | Canine, Human, Mouse, Porcine, Rat |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Peptide with sequence C-EMVLHKVLFPGRDY, from the internal region of the protein sequence according to NP_620708.1; NP_620709.1. |
Specificity | This antibody is expected to recognize isoforms beta 1 and beta 2 of JNK2 (NP_620708.1, NP_620709.1). |
Formulation | Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 48.3 kDa (NP_620709.1). |
Database Link | |
Background | c-Jun amino terminal kinases (JNKs) are MAP kinase family members that differ from other MAP kinases in that they are phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53. |
Synonyms | JNK-55, PRKM9, MAP kinase 9 |
Reference Data |
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