GDNF Receptor alpha 1 (GFRA1) Chicken Polyclonal Antibody

CAT#: AP33455PU-N

GDNF Receptor alpha 1 (GFRA1) chicken polyclonal antibody, Aff - Purified


USD 435.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Applications ELISA, IF, WB
Recommended Dilution ELISA: 1/80000-1/160000. 
Western blot: 1/5000-1/10000.
Immunofluorescence: 1/1000-1/2000.
Reactivities Human
Host Chicken
Isotype IgY
Clonality Polyclonal
Immunogen Recombinant His-tagged human GFRa-1 protein produced using CHO-based.
For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant.
Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.
Specificity This antibody detects Human GFRa-1 and doesn’t cross-react with hGFRa-2, hGFRa-3, hGFRa-4.
Other species not tested.
Formulation Concentrated Ammonium Sulphate in PBS pH 7.4
State: Aff - Purified
State: Liquid purified IgY fraction
Concentration lot specific
Purification Affinity Chromatography
Storage Upon receipt, store at 2-8°C.
As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use.
Stability Shelf life: One year from despatch.
Background Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674).
Synonyms GFR-alpha-1, GDNF receptor alpha, RET ligand 1, GDNFRA, RETL1, TRNR1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.