GFRA4 / GDNFR-alpha 4 Chicken Polyclonal Antibody
Specifications
Product Data | |
Applications | ELISA, IF, WB |
Recommended Dilution | ELISA: 1/160000-1/320000. Western blot: 1/5000-1/10000. Immunofluorescence: 1/1000-1/3000. |
Reactivities | Human |
Host | Chicken |
Isotype | IgY |
Clonality | Polyclonal |
Immunogen | Recombinant His-tagged human GFRa-4 protein produced using CHO-based. For production of hGFRa-4, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant. |
Specificity | This antibody detects Human GFRa-4 and doesn’t cross-react with hGFRa-1, hGFRa-2, hGFRa-3. Other species not tested. |
Formulation | PBS pH 7.4 State: Aff - Purified State: Liquid purified IgY fraction Preservative: 0.09% Sodium Azide |
Concentration | 1.0 mg/ml |
Purification | Immunoaffinity Chromatography |
Background | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674). |
Synonyms | GFR-alpha-4, Persephin receptor, GDNF receptor alpha-4 |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.