ALKBH1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP46320PU-N

ALKBH1 (N-term) rabbit polyclonal antibody, Aff - Purified


USD 445.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution

Western blotting (0.2 - 1 µg/ml).

Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a N-terminal region of human ALKBH1
Formulation State: Aff - Purified
State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification Immunoaffinity column
Predicted Protein Size ALX1: 37 kDa
Gene Name Homo sapiens alkB homolog 1, histone H2A dioxygenase (ALKBH1)
Background ALKBH1 is a dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. This requires molecular oxygen, alpha-ketoglutarate and iron. ALKBH1 may have a role in placental trophoblast lineage differentiation, has DNA lyase activity and introduces double-stranded breaks at abasic sites. It cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.
Synonyms ALKBH, ABH
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.