alpha 2 Macroglobulin (A2M) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50006PU-N

alpha 2 Macroglobulin (A2M) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

A2M Antibody (C-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the A2M antibody detected the A2M protein (arrow)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1161-1192 amino acids from the C-terminal region of human A2M
• Specificity: This antibody reacts to Alpha-2-macroglobulin.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens alpha-2-macroglobulin (A2M)
• Database Link:
  Entrez Gene 2 Human
• Background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
• Synonyms: Alpha-2-M, CPAMD5, Alpha 2 macroglobulin
• Note: Molecular Weight: 163291 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades