Aminoadipate aminotransferase (AADAT) (Center) Rabbit Polyclonal Antibody

CAT#: AP50010PU-N

Aminoadipate aminotransferase (AADAT) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

AADAT Antibody (Center) western blot analysis in HepG2, Y79 cell line lysates (35ug/lane).This demonstrates the AADAT antibody detected the AADAT protein (arrow)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELIS: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 203-232 amino acids from the Central region of human AADAT
• Specificity: This antibody reacts to AADAT.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 1
• Database Link:
  Entrez Gene 51166 Human
• Background: This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.
• Synonyms: KAT2, Kynurenine aminotransferase II, Kynurenine-oxoglutarate aminotransferase II, Kynurenine-oxoglutarate transaminase II, 2-aminoadipate transaminase, 2-aminoadipate aminotransferase, Alpha-aminoadipate aminotransferase
• Note: Molecular Weight: 47352 Da

Reference Data

• Protein Pathways: Lysine biosynthesis, Lysine degradation, Metabolic pathways, Tryptophan metabolism