ABCD2 (Center) Rabbit Polyclonal Antibody

CAT#: AP50018PU-N

ABCD2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of ABCD2 Antibody (Center) in mouse brain tissue lysates (35 ug/lane). ABCD2 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 276~306 amino acids from the Central region of human ABCD2.
• Specificity: This antibody reacts to ABCD2.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ATP binding cassette subfamily D member 2 (ABCD2)
• Database Link:
  Entrez Gene 26874 MouseEntrez Gene 225 Human
• Background: ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.
• Synonyms: Adrenoleukodystrophy-related protein, Adrenoleukodystrophy-like 1, ALD1, ALDL1, ALDRP
• Note: Molecular Weight: 83233 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: ABC transporters