ACTL7B (N-term) Rabbit Polyclonal Antibody

CAT#: AP50070PU-N

ACTL7B (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

ACTL7B Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ACTL7B antibody detected the ACTL7B protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human ACTL7B
• Specificity: This antibody reacts to ACTL7B.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens actin like 7B (ACTL7B)
• Database Link:
  Entrez Gene 10880 Human
• Background: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
• Synonyms: Actin-like-7-beta; Tact1
• Note: Molecular Weight: 45234 Da