AKR1C4 (N-term) Rabbit Polyclonal Antibody

CAT#: AP50134PU-N

AKR1C4 (N-term) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

Product Images

Other products for "AKR1C4"

Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1/1000.
Western blotting: 1/100 - 1/500.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human AKR1C4.
Specificity This antibody reacts to AKR1C4.
Formulation PBS containing 0.09% (W/V) sodium azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein A
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens aldo-keto reductase family 1 member C4 (AKR1C4)
Background AKR1C4 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Synonyms Chlordecone reductase, CDR, CHDR, 3-alpha-HSD1, Dihydrodiol dehydrogenase 4, DD4, DD-4, HAKRA
Note Molecular Weight: 37067 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Primary bile acid biosynthesis

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.