AKR1D1 (Center) Rabbit Polyclonal Antibody

CAT#: AP50135PU-N

AKR1D1 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

AKR1D1 Antibody (Center) western blot analysis in 293 cell line lysates (35 ug/lane).This demonstrates the AKR1D1 antibody detected the AKR1D1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 110-139 amino acids from the Central region of human AKR1D1
• Specificity: This antibody reacts to AKR1D1.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens aldo-keto reductase family 1, member D1 (AKR1D1), transcript variant 1
• Database Link:
  Entrez Gene 6718 Human
• Background: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
• Synonyms: 3o5bred; CBAS2; SRD5B1
• Note: Molecular Weight: 37377 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways, Primary bile acid biosynthesis