Angiopoietin 2 (ANGPT2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50176PU-N

Angiopoietin 2 (ANGPT2) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

ANGPT2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ANGPT2 antibody detected the ANGPT2 protein (arrow).

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  ANGPT2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the ANGPT2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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  ANGPT2 Antibody (C-term) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
  Immunohistochemistry: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 409-440 amino acids from the C-terminal region of human ANGPT2
• Specificity: This antibody reacts to Angiopoietin-2.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens angiopoietin 2 (ANGPT2), transcript variant 2
• Database Link:
  Entrez Gene 285 Human
• Background: The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
• Synonyms: ANG-2, ANG2, ANGPT2
• Note: Molecular Weight: 56919 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein