AP3S1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP50203PU-N

AP3S1 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

AP3S1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the AP3S1 antibody detected the AP3S1 protein (arrow).

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  AP3S1 Antibody (N-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the AP3S1 antibody detected the AP3S1 protein (arrow).

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  AP3S1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AP3S1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
  Immunohistochemistry: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human AP3S1
• Specificity: This antibody reacts to AP3 complex subunit sigma-1.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens adaptor related protein complex 3 sigma 1 subunit (AP3S1), transcript variant 1
• Database Link:
  Entrez Gene 11777 MouseEntrez Gene 1176 Human
• Background: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
• Synonyms: CLAPS3, Sigma-adaptin 3a, Sigma-3A-adaptin, Sigma 3A Adaptin
• Note: Molecular Weight: 21732 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysosome