BCL2A1 (Center) Rabbit Polyclonal Antibody

CAT#: AP50357PU-N

BCL2A1 (Center) rabbit polyclonal antibody, Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications FC, IHC, WB
Recommended Dilution ELISA: 1/1000.
Western blotting: 1/50 - 1/100.
Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Flow cytometric: 1/10 - 1/50.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 63~92 amino acids from the Center region of human BCL2A1
Specificity This antibody reacts to Bcl-2-like 5.
Formulation PBS containing 0.09% (W/V) sodium azide as preservative
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein A
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens BCL2 related protein A1 (BCL2A1), transcript variant 1
Background Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
Synonyms BCL2A1, BCL2L5, BFL1, GRS, HBPA1, Bcl-2-like protein 5, Protein BFL-1
Note Molecular Weight: 20132 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.