Bcl 7A (BCL7A) (N-term) Rabbit Polyclonal Antibody
Other products for "BCL7A"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. Western blotting: 1/100 - 1/500. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A |
Specificity | This antibody reacts to Bcl-7A. |
Formulation | PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens B-cell CLL/lymphoma 7A (BCL7A), transcript variant 2 |
Database Link | |
Background | This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. |
Synonyms | BCL7A |
Note | Molecular Weight: 22810 Da |
Reference Data | |
Protein Families | Druggable Genome |
Documents
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