BPNT1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP50387PU-N

BPNT1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

BPNT1 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the BPNT1 antibody detected the BPNT1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human BPNT1
• Specificity: This antibody reacts to BPNT1.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1), transcript variant 1
• Database Link:
  Entrez Gene 10380 Human
• Background: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
• Synonyms: BPntase; PAP-inositol-1,4-phosphatase; PIP
• Note: Molecular Weight: 33392 Da

Reference Data

• Protein Pathways: Sulfur metabolism