CACNB1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP50704PU-N

CACNB1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

CACNB1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CACNB1 antibody detected the CACNB1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 542-572 amino acids from the C-terminal region of human CACNB1
• Specificity: This antibody reacts to CACNB1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 65714 Da
• Gene Name: calcium voltage-gated channel auxiliary subunit beta 1
• Database Link:
  Entrez Gene 782 Human
  UniProt ID Q02641
• Background: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
• Synonyms: CAB1, CACNLB1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway