CACNB2 (Center) Rabbit Polyclonal Antibody

CAT#: AP50705PU-N

CACNB2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

CACNB2 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CACNB2 antibody detected the CACNB2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 231-261 amino acids from the Central region of human CACNB2.
• Specificity: This antibody reacts to CACNB2.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 73581 Da
• Gene Name: Homo sapiens calcium voltage-gated channel auxiliary subunit beta 2 (CACNB2), transcript variant 1
• Database Link:
  Entrez Gene 783 Human
• Background: This gene encodes a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome which is an autoimmune disorder. Mutations in this gene are associated with Brugada symdrome. Alternatively spliced variants have been identified for this gene.
• Synonyms: CAB2, CACNLB2, MYSB

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway