Calcitonin (CALCA) (Center) Rabbit Polyclonal Antibody

CAT#: AP50713PU-N

Calcitonin (CALCA) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

CALCA Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CALCA antibody detected the CALCA protein (arrow).

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  CALCA Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CALCA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human CALCA
• Specificity: This antibody reacts to CALCA.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 13898 Da
• Gene Name: Homo sapiens calcitonin related polypeptide alpha (CALCA), transcript variant 3
• Database Link:
  Entrez Gene 796 Human
• Background: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I

Reference Data

• Protein Families: Druggable Genome, Secreted Protein