Cyclin G2 (CCNG2) (Center) Rabbit Polyclonal Antibody

CAT#: AP50814PU-N

Cyclin G2 (CCNG2) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

CCNG2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CCNG2 antibody detected the CCNG2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/1000
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 214-243 amino acids from the Central region of human CCNG2
• Specificity: This antibody reacts to CCNG2.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 38866 Da
• Gene Name: cyclin G2
• Database Link:
  Entrez Gene 901 Human
  UniProt ID Q16589
• Background: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.
• Synonyms: Cyclin-G2, CCNG2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: p53 signaling pathway