CTBP2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP51117PU-N

CTBP2 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CTBP2 (arrow) using CTBP2 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CTBP2 gene.

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  Formalin fixed, paraffin embedded human rectum tissue stained with CTBP2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CTBP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-150.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human CTBP2.
• Specificity: This antibody recognizes Human CTBP2 (N-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens C-terminal binding protein 2 (CTBP2), transcript variant 3
• Database Link:
  Entrez Gene 1488 Human
• Background: This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD⁺ binding domain similar to NAD⁺-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. [provided by RefSeq].
• Synonyms: C-terminal-binding protein 2
• Note: Molecular Weight: 48945 Da

Reference Data

• Protein Families: Stem cell - Pluripotency, Stem cell relevant signaling - Wnt Signaling pathway
• Protein Pathways: Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway