CTSA (N-term) Rabbit Polyclonal Antibody

CAT#: AP51129PU-N

CTSA (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

CTSA Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CTSA antibody detected the CTSA protein (arrow).

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  CTSA Antibody (N-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the CTSA antibody detected the CTSA protein (arrow).

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  CTSA antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CTSA antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 25-53 amino acids from the N-terminal region of human CTSA
• Specificity: This antibody reacts to CTSA.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 54466 Da
• Gene Name: Homo sapiens cathepsin A (CTSA), transcript variant 1
• Database Link:
  Entrez Gene 19025 MouseEntrez Gene 5476 Human
• Background: CTSA encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. The formation of this complex provides a protective role for stability and activity. Deficiencies in this gene are linked to multiple forms of galactosialidosis.
• Synonyms: Carboxypeptidase L, Carboxypeptidase C, CTSA, PPGB, PPCA

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Renin-angiotensin system