CysLT1 (CYSLTR1) (Center) Rabbit Polyclonal Antibody

CAT#: AP51175PU-N

CysLT1 (CYSLTR1) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CYSLTR1 Antibody (Center) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the CYSLTR1 antibody detected the CYSLTR1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of Human CYSLTR1.
• Specificity: This antibody recognizes Human CYSLTR1 (Center).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens cysteinyl leukotriene receptor 1 (CYSLTR1), transcript variant 3
• Database Link:
  Entrez Gene 10800 Human
• Background:
  
  

  The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.

  
  
• Synonyms: Cysteinyl leukotriene receptor 1, CysLTR1, LTD4 receptor, HG55, HMTMF81
• Note: Molecular Weight: 38541 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction