DDX3Y (N-term) Rabbit Polyclonal Antibody

CAT#: AP51221PU-N

DDX3Y (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of DDX3Y Antibody (N-term) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the DDX3Y antibody detected the DDX3Y protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 97-127 amino acids from the N-terminal region of human DDX3Y.
• Specificity: This antibody recognizes Human DDX3Y (N-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens DEAD-box helicase 3, Y-linked (DDX3Y), transcript variant 1
• Database Link:
  Entrez Gene 8653 Human
• Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified.
• Synonyms: DBY, DEAD box protein 3 Y-chromosomal
• Note: Molecular Weight: 73154 Da

Reference Data

• Protein Pathways: RIG-I-like receptor signaling pathway