Dopamine D2 Receptor (DRD2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51318PU-N

Dopamine D2 Receptor (DRD2) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Dopamine D2 receptor Antibody (C-term) in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates the DRD2 antibody detected the DRD2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 306-336 amino acids from the C-terminal region of Human Dopamine D2 receptor.
• Specificity: This antibody recognizes Human and Mouse Dopamine D2 receptor (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens dopamine receptor D2 (DRD2), transcript variant 1
• Database Link:
  Entrez Gene 1813 Human
• Background: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
• Synonyms: DRD2
• Note: Molecular Weight: 50619 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Gap junction, Neuroactive ligand-receptor interaction