Desmocollin 3 (DSC3) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51323PU-N

Desmocollin 3 (DSC3) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of DSC3 Antibody (C-term) in mouse spleen tissue lysates (35ug/lane). This demonstrates the DSC3 antibody detected the DSC3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Peptide ELISA: 1/1,000.
  Western Blot: 1/1,000.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of Human Desmocollin-3.
• Specificity: This antibody recognizes Human and Mouse Desmocollin-3 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens desmocollin 3 (DSC3), transcript variant Dsc3a
• Database Link:
  Entrez Gene 13507 MouseEntrez Gene 1825 Human
• Background:
  The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
• Synonyms: Desmocollin-4, HT-CP, DSC3, CDHF3, DSC4
• Note: Molecular Weight: 99969 Da

Reference Data

• Protein Families: Transmembrane