DUOX2 (Center) Rabbit Polyclonal Antibody

CAT#: AP51336PU-N

DUOX2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Dual oxidase 2 Antibody in CEM cell line lysates (35ug/lane). This demonstrates the DUOX2 antibody detected the DUOX2 protein (arrow).

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  Flow cytometric analysis of CEM cells using Dual oxidase 2 Antibody (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution:

  Western Blot: 1/1000.
  Flow Cytometry: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of human DUOX2
• Specificity: This antibody recognizes Human Dual oxidase 2 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A followed by peptide affinity purification.
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens dual oxidase 2 (DUOX2)
• Database Link:
  Entrez Gene 50506 Human
• Background: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
• Synonyms: Large NOX 2, Long NOX 2, Thyroid oxidase 2, p138 thyroid oxidase, LNOX2, THOX2
• Note: Molecular Weight: 175364 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane