EGLN2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP51387PU-N

EGLN2 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

EGLN2 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the EGLN2 antibody detected the EGLN2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 95-123 amino acids from the N-terminal region of human EGLN2
• Specificity: This antibody reacts to EGLN2.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 43650 Da
• Gene Name: Homo sapiens egl-9 family hypoxia inducible factor 2 (EGLN2), transcript variant 1
• Database Link:
  Entrez Gene 112398 Human
• Background: The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this posttranslational modification. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Synonyms: HIF-PH1, HIF PH1, HPH-1, HPH-3, EIT6

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Pathways in cancer, Renal cell carcinoma