KDM2B (N-term) Rabbit Polyclonal Antibody

CAT#: AP51620PU-N

KDM2B (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of FBXL10b (N-term) in mouse bladder tissue lysates (35ug/lane). This demonstrates the FBXL10b antibody detected the FBXL10b protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human cervical tissue reacted with FBXL10b (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human FBXL10b
• Specificity: This antibody recognizes Human and Mouse FBXL10b (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens lysine demethylase 2B (KDM2B), transcript variant 2
• Database Link:
  Entrez Gene 30841 MouseEntrez Gene 84678 Human
  UniProt ID Q8NHM5
• Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
• Synonyms: Uncharacterized protein,KDM2B
• Note: Molecular Weight: Isoform 74kd; 144769 Da

Reference Data

• Protein Families: Druggable Genome