FBXO2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51626PU-N

FBXO2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of FBXO2 Antibody (C-term) in mouse brain tissue and HepG2, 293 cell line lysates (35ug/lane). This demonstrates the FBXO2 antibody detected the FBXO2 protein (arrow)

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  Flow cytometric analysis of HepG2 cells using FBXO2 Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 251-279 amino acids from the C-terminal region of human FBXO2
• Specificity: This antibody recognizes Human and Mouse FBXO2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens F-box protein 2 (FBXO2)
• Database Link:
  Entrez Gene 230904 MouseEntrez Gene 26232 Human
• Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state.
• Synonyms: F-box only protein 2, FBX2
• Note: Molecular Weight: 33328 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis