Emi1 (FBXO5) (Center) Rabbit Polyclonal Antibody

CAT#: AP51634PU-N

Emi1 (FBXO5) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of FBXO5 Antibody (Center) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the FBXO5 antibody detected the FBXO5 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 191-221 amino acids from the Central region of Human FBXO5.
• Specificity: This antibody recognizes Human FBXO5 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens F-box protein 5 (FBXO5), transcript variant 2
• Database Link:
  Entrez Gene 26271 Human
• Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: F-box only protein 5, EMI1, FBX5
• Note: Molecular Weight: 50146 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Oocyte meiosis